Synthesis of Conformationally restricted amino acids – Highly versatile scaffolds.
Stereoselektive Synthese von Naturstoffanaloga ausgehend von anti-substituierten γ-Butyrolactonen.
Die ‘Click’-Reaktion als Werkzeug zur Synthese von homogenen und heterogenen Organokatalysatoren.
Studies Towards Synthesis of Biologically Active Guaianolides: Enantioselective Total Synthesis of (+)-Arglabin.
Immobilization of Homogeneous Catalysts on Nanoparticles and their Application in Semi-Heterogeneous Catalysis.
Synthesis and exploration of chiral aza-bis(oxazolines) and organocatalysts in asymmetric reactions.
Synthesis and exploration of chiral aza-bis(oxazolines) and organocatalysts in asymmetric reactions.
Synthesis and Conformational Analysis of Peptidomimetics Containing Unnatural Amino Acids Based on a Diketopiperazinone and γ-Butyrolactone Scaffold.
Synthesis of Conformationally Restricted Amino Acids and their Use in the Preparation of Biologically Active Peptides and Peptidomimetics.
Design, synthesis and structural evaluation of peptidomimetics towards foldamers, PNAs and non covalent inhibitors of the 20S proteosome.
Design, synthesis and structural evaluation of peptidomimetics with a defined secondary structure.
Entwicklung einer Diversitäts-orientierten Synthesestrategie an einem tricyclischen γ-Butyrolacton-Naturstoffanaloga.
Chiral Oxazoline and Bis(oxazoline) Ligands – New biomimetic Models for Iron Containing Nonheme Proteins and Their Application in Catalysis.
Studies towards the total synthesis of biological γ-butyrolactones.
Development of new methods fort he synthesis of pharmacologically active compounds. Synthesis of new immobilized homo- and heterogeneous catalysts for the chemoselective oxidation of alcohols.
Darstellung von asymmetrisch substituierten Tetrahydrofuranen als Bausteine in der Naturstoffsynthese.
Stereoselective Synthesis of 1,2-Cyclopropane-carboxylated Furanoids: Applications towards the Preparation of Marine Natural Products and Unnatural Amino Acids.
Asymmetric Synthesis and Histamine Receptor Activity of New H1-Receptor Agonists and Conformationally Restricted H3-Receptor Antagonists.
Asymmetric methodologies for the construction of 5,7,5- and 6,6,6-tricyclic sesquiterpene lactones towards the synthesis of Arglabin.
Synthese und Immobilisierung neuer Aza-bis(oxazolin)liganden und deren Anwendung in der asymmetrischen Katalyse.
Synthese und Einsatz neuer Oxazolin-Liganden in der asymmetrischen Katalyse.
Synthesis, conformational investigation and applications of α-peptides containing cis-β-aminocyclo-propane dicarboxylic acids.
Enantioselective synthesis of new conformationally constrained sugar-like γ-, δ-, ε-amino acids, δ-peptides and nucleoside amino acids.
The synthesis of the new 3-piperidinol chiral building blocks from substituted pyridines and the synthesis of new vitamin C analogues.
Enantioselektive Synthese bi- und trizyklischer γ-Butyrolacton Naturstoff-Analoga.
Synthese von polyhydroxilierten Indolizidinalkaloiden und γ-Aminosäuren.