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19. "Hole-Mediated PhotoRedox Catalysis: Tris(p-Substituted)biarylaminium Radical Cations as Tunable, Precomplexing and Potent Photooxidants"

S. Wu, J. Zurauskas, M. Domanski, P. Hitzfeld, V. Butera, D. J. Scott, J. Rehbein, A. Kumar, E. Thyrhaug, J. Hauer, J. P. Barham* 

Org. Chem. Front. 2021, 8, 1132-1142 PDF

(Selected for the Outside Back Cover for Issue 6, 2021)

OCF cover Ar3N


18. "Photocatalyst-Free, Visible-Light-Mediated C(sp3)-H Arylation of Amides via a Solvent-Caged EDA Complex"

J. Kaur, A. Shahin, J. P. Barham*

Org. Lett. 2021, 6, 2002-2006  PDF

(Selected as a Supplementary Cover for Issue 6, 2021)

OL EDA cover


17. "Photocatalytic (Hetero)Arylation of C(sp3)-H Bonds with Carbon Nitride" 

S. Das, K. Murugesan, G. J. V. Rodríguez, J. Kaur, J. P. Barham, A. Savateev, M. Antonietti, B. König*

ACS Catal. 2021, 11, 1593-1603  PDF


16. "C-Alkylation of alkali metal carbanions with olefins"

M. J. P. Mandigma, M. Domanski, J. P. Barham* Org. Biomol. Chem. 202018, 7697-7723  PDF 

(Selected as the Outside Front Cover for Issue 39, 2020)



15. "Photosensitized direct C-H fluorination and trifluoromethylation in organic synthesis"

S. Yakubov, J. P. Barham* Beilstein J. Org. Chem. 2020, 16, 2151-2192  PDF TOC photofluor

14. "Base-catalyzed C-alkylation of potassium enolates with styrenes via a Metal-ene Reaction: A Mechanistic Study"

J. P. Barham,* T. Fouquet, Y. Norikane, Org. Biomol. Chem. 2020, 18, 2063-2075  PDF 

(Selected as the Outside Front Cover for Issue 11, 2020)

OBC CAKES front cover


13. "Synthetic Photoelectrochemistry" 

J. P. Barham,* B. König, Angew. Chem. Int. Ed. 2020, 59, 11732-11747 PDF

(Invited contribution) (ESI Highly Cited)

ACIE SynthPEC Cover


12. "High Efficiency Microwave Flow Chemistry Toward Synthesis of Functional Materials and Pharmaceutical Cores"

J. P. Barham,* E. Koyama, J. Sugiyama, Y. Norikane, H. Egami, Y. Hamashima AMPERE 2019, 17th International Conference on Microwave and High Frequency Heating, In Press PDF


11. "Microwave Flow: A Perspective on Reactor and Microwave Configurations and the Emergence of Tunable Single-mode Heating Towards Large-scale Applications"

J. P. Barham,* E. Koyama, Y. Norikane, N. Ohneda, T. Yoshimura,* Chem. Rec. 2019, 19, 188-203. PDF 

Chem Rec MWflow Cover

10. "A Continuous-Flow Resonator-Type Microwave Reactor for High-Efficiency Organic Synthesis and Claisen Rearrangement as a Model Reaction"

E. Koyama,* N. Ito, J. Sugiyama, J. P. Barham, Y. Norikane, N. Ohneda, Y. Ohno, T. Yoshimura, H. Odajima, T. Okamoto, J. Flow Chem. 20188, 147-156. PDF 

JFC cover created

9. "C-alkylation of N-alkylamines with styrenes in air and scale-up using a microwave flow reactor"

J. P. Barham,* S. Tamaoki, H. Egami, N. Ohneda, T. Okamoto, H. Odajima, Y. Hamashima,* Org. Biomol. Chem. 201816, 7568-7573. PDF 

OBC C-alk amide flow TOC

8. "Regio- and chemoselective Csp3-H arylation of benzylamines by single electron transfer/hydrogen atom transfer synergistic catalysis"

T. Ide, J. P. Barham, M. Fujita, Y. Kawato, H. Egami, Y. Hamashima,* Chem. Sci. 2018, 9, 8453-8460. PDF


7. "Dual Roles for Potassium Hydride in Haloarene Reduction: CSNAr and SET Reduction via Organic Electron Donors Formed in Benzene"

J. P. Barham, S. E. Dalton, M. Allison, G. Nocera, A. Young, M. P. John, T. M. McGuire, S. Campos, T. Tuttle,* J. A. Murphy,* J. Am. Chem. Soc. 2018, 140, 11510-11518. PDF 


6. "Selective, Scalable Synthesis of C60-Fullerene/Indene Monoadducts Using a Microwave Flow Applicator"

J. P. Barham,* S. Tanaka, E. Koyama, N. Ohneda, T. Okamoto, H. Odajima, J. Sugiyama, Y. Norikane,* J. Org. Chem. 2018, 83, 4348-4354. PDF 

JOC Fullerene TOC

5. "Contra-thermodynamic Hydrogen Atom Abstraction in the Selective C-H Functionalization of Trialkylamine N-CH3 Groups"

J. P. Barham, M. P. John, J. A. Murphy,* J. Am. Chem. Soc. 2016, 138, 15482-15487. PDF

(Featured in the top 20 ‘most read articles’ of JACS in 2016. Recognised by the 2017 Reaxys Ph.D. Prize)


4. "KOtBu: A Privileged Reagent for Electron Transfer Reactions?"

J. P. Barham, G. Coulthard, K. J. Emery, E. Doni, F. Cumine, G. Nocera, M. P. John, L. E. A. Berlouis, T. McGuire, T. Tuttle,* J. A. Murphy,* J. Am. Chem. Soc. 2016, 138, 7402-7410. PDF

(Featured in the top 20 ‘most read articles’ of JACS in 2016. Features on the first page of Google Entries for ‘KOtBu’. Features as a ‘Highly Cited Paper’ (top 1% of its academic field) in Web of Science)


3. "Double Deprotonation of Pyridinols Generates Potent Organic Electron-Donor Initiators for Haloarene-Arene Coupling"

J. P. Barham, G. Coulthard, R. G. Kane, N. Delgado, M. P. John, John A. Murphy,* Angew. Chem. Int. Ed. 2016, 55, 4492-4496. PDF  

(Featured in the top 15 ‘most accessed articles’ of ACIE in 03.2016)

ACIE Pyridinols TOC

2. "Asymmetric Intramolecular Conjugate Addition Nitro-Mannich Route to cis-2-Aryl-3-nitrotetrahydroquinolines"

J. C. Anderson,* J. P. Barham, C. D. Rundell, Org. Lett. 2015, 17, 4090-4093. PDF 

OL NitroMannich TOC

1. "One-pot Functionalisation of N-Substituted Tetrahydroisoquinolines by Photooxidation and Tunable Organometallic Trapping of Iminium Intermediates"

J. P. Barham, M. P. John, J. A. Murphy,* Beilstein J. Org. Chem. 2014, 10, 2981-2988. PDF 


Book Chapters

1. "Heating Applications: Flow Chemistry"

J. P. Barham,* E. Koyama, Y. Norikane, T. Yoshimura,*

in "RF Power Semiconductor Generator Application in Heating and Energy Utilization" 

Editors: S. Horikoshi, N. Serpone, 2020, pp 91-117, ISBN: 978-981-15-3546-5 



1. "Photoresponsive azo compound and polymer compound"

Y. Yue, Y. Norikane, E. Koyama, J. P. Barham

Japan Patent Office (Applicant: National Institute of Advanced Industrial Science and Technology. Institution Number: 301021533. Application Number: PCT/JP2019/010828. Filing Date: 19/02/2019)

Press Releases

1. "Enabling High-efficiency Synthesis of Organic Materials with a Flow-type Microwave Synthesiser"

National Institute of Advanced Industrial Science and Technology (AIST) Press Release, 12/04/2018.

For the Summary (English)

For the Press Release (Japanese)

(Featured in newspaper: Kagaku Kogyou Nippou (Japan Chemical Daily), 13/04/2018, 1st page. Featured in Nikkei Sangyo Shimbun, 19/04/2018, 5th page)

Blogs & Webinars

2. "Seven strategies for scientists fo communicate their research and create a brand" 

J. P. Barham

For the Webinar

For the Summary

1. "Exploring continuous flow chemistry"

J. P. Barham

For the Blog

  1. Fakulty of Chemistry and Pharmacy
  2. Institute of Organic Chemistry

Joshua Barham



Sofja Kovalevskaja Group Leader

Office: CH 23.2.80

Phone +49 (0)941 943-4373